It's finally time to start the season, and I'm calling for shootout conditions with a 100 percent chance of offense. For the most part, if you have guys going tonight, you'll want to login and make sure they're in the lineup so you don't spend the next week and a half kicking yourself.

But there are a few key factors to take into consideration before you set that lineup, so let's take a look at the first edition of the Gameday4Cast.

QUARTERBACK

If you're thinking twice about whether Drew Brees should be in your lineup, you should have your fantasy football card taken away, if there were such a thing. Brees is a must-play every week.

Brett Favre's situation tonight is a bit different. Favre struggled against the Saints in last year's playoffs, and it's yet to be seen how well his bum ankle will hold up over the course of an entire game. If you have a viable option, let Favre sit for a week to see how he performs.

RUNNING BACK

Like Brees, Adrian Peterson should be in your lineup every week, unless you got confused and plucked the other Adrian Peterson off the waiver wire, in which case, you and the guy who benched Brees can play in the same league together next year.

On the other sideline, don't expect too much from Pierre Thomas and Reggie Bush. Minnesota boasted the league's second-best run defense last year, so the Saints are likely to lean on their potent passing game. Both Thomas and Bush do take a slight up-tick with third-stringer Chris Ivory out, though.

WIDE RECEIVER

Marques Colston is listed as probable, so it's safe to start him. As for the rest of the Saints' receivers, if they're worth owning, they're probably worth starting. That goes for Robert Meachem and Devery Henderson, and maybe even Lance Moore if you're desperate.

The Vikings' receiver situation is murky with Sidney Rice out and Percy Harvin suffering from splitting migraines. It seems Harvin will play, but he's a risky start, leaving Bernard Berrian as the best option and Greg Camarillo as a desperation play in the deepest of leagues.

TIGHT END

The Vikings' bad receiver situation is a plus for Visanthe Shiancoe, who should get plenty of looks from Favre, especially in the red zone, where Rice's absence will be a huge factor.

Saints tight end Jeremy Shockey has been banged up. He will play, but you probably don't want him in your lineup this week.

THE SKINNY

Look for the Saints' passing game to pick up where it left off a year ago, resulting in a big night for Brees and his receiving corps. Expect the expected from Peterson -- a big night on the ground -- and temper your expectations surrounding Favre and Minnesota's depleted passing game.